Department of Bioorganic chemistry

Медицински университет - Пловдив
Медицински университет – Пловдив


e-mail : [email protected]
Phone numbers :
032/200691 – Assoc. prof. Stela Dimitrova, PhD – Head of Department
032/200692 – Assoc. prof. Yordanka Uzunova, PhD
032/200693 – Assistant professors
032/200694 – Laboratory assistants

Academic Staff

Associate professor Stela Dimitrova, PhD – Head of Department

Phone : 032/200691
e-mail: [email protected]

Professor Rumen Mladenov, PhD

Phone :
e-mail: [email protected]

Associate professor Yordanka Uzunova, PhD

Phone : 032/200692
e-mail: [email protected]

Associate professor Plamen Stoyanov, PhD

Phone :
e-mail: [email protected]

Chief assistant professor Mariana Katsarova, PhD

Phone :032/200693
e-mail: [email protected]

Assistant professor Mariya Vlasheva

Phone : 032/200693
e-mail: [email protected]

Assistant professor Miglena Milusheva

Phone : 032/200693
e-mail: [email protected]

Assistant professor Nikolay Toshev, PhD

Nikolaj Toshev
Phone :
e-mail: [email protected]

Ekaterina Georgieva – chemist
Yordanka Alexieva – laboratory assistant
Svetla Kostadinova – laboratory assistant
Aynur Yusein – hygienist
Katiya Papalova – hygienist


The current research topics in the Department of Bioordanic Chemistry are related to:

– Chemical composition and biological activity of medicinal plants
– Biopolymers in medicine
– Analysis of metabolites in biological samples


1. Labbook for practical classes in Bioorganic chemistry, M. Argirova, Y. Uzunova, ISBN 978-954-9549-28-7, First edition, Plovdiv 2015.


1. Dimitrova S, Pavlova K, Lukanov L, Savova I. Chemical composition of lipids and other lipophilic compounds from antarctic yeast strains. Comptes rendus de l’Academie bulgare des Sciences, 2008, 61(4), 481-486. IF 0.152

2. Uzunova Y, Lukanov L, Filipov I, Vladimirov S. High-performance liquid chromatographic determination of unreacted monomers and other residues contained in dental composites. JBBM 2008; 70: 883-888 IF 1.994

3. Sarafian V.S, Uzunova Y, Hayrabedyan S, Ganchevska P, Filipova M, Filipov I, Lukanov L, Vladimirov S. Histo-blood group antigen expression and proliferative acrtivity of fibroblasts treated with dental monomers. Cell Biol Toxicol 2008; 24: 27-37 IF 2.155

4. Dimitrova S, Pavlova K, Lukanov L, Zagorchev P. Synthesis of coenzyme Q10 and β-carotene by yeasts isolated from antarctic soil and lichen in response to ultraviolet and visible radiations. Appl Biochem Biotechnol, 2010, 162, 795-804. IF 1.879

5. Uzunova Y, Lukanov L, Vasileva P, Filipov I. Spectroscopic, chromatographic and morphological study of photopolymerized dental composites. Digest Journal of Nanomaterials and Biostructures 2012; 7(4):1825-1832 IF 1.200

6. Dimitrova S, Pavlova K, Lukanov L, Korotkova E, Petrova E, Zagorchev P, Kuncheva M. Production of metabolites with antioxidant and emulsifying properties by antarctic strain Sporobolomyces salmonicolor AL1. Appl Biochem Biotechnol, 2013, 169, 301-311. IF 1.687

7. Rusinova-Videva S, Dimitrova S, Georgieva K, Kacarova M, Pavlova K. Effect of Zn2+, Cu2+ and Fe2+ ions for bioaccumulation of ergosterol, β-carotene and coenzyme Q10 by antarctic yeast strain Sporobolomyces salmonicolor AL1. Comptes rendus de l’Academie bulgare des Sciences, 2016 IF 0. 233

8. Кatsarova М, Dimitrova S, Lukanov L, Sadakov F Determination of phenolic acids, flavonoids, terpenes and ecdysteroids in medicinal plant extracts and food supplements. Comptes rendus de l’Academie bulgare des sciences, 2017, 70(7), 947-956 IF 0.270

9. Кatsarova М, Dimitrova S, Lukanov L, Sadakov F, Denev P, Plotnikov E, Kandilarov I, Kostadinova I. Antioxidant activity and nontoxicity of extracts from Valeriana officinalis, Melissa officinalis, Crataegus monogyna, Hypericum perforatum, Serratula coronatа and combinations antistress 1 and antistress 2. Bulgarian Chemical Communications, 2017, Vol. 49, Special Issue G, 93-98 IF 0.242

10. Todorova V, Filipov I, Uzunova Y. Penetration of an Infiltrant and an Adhesive into Natural Proximal Noncavitated Caries Lesions – a Comparative In
Vitro Study 2019 SYLWAN., 163(9) 487-505

11. Exner G, Marudova M, Sotirov S, Marinova A, Viraneva A, Pilicheva B, Bodurov I, Vlaeva I, Uzunova Y, Yovcheva T, Multilayered polyelectrolyte structures with potential for intracavity drug delivery systems, Applied Surface ScienceVolume 493, 1 November 2019, Pages 620-627

12. Marudova M, Exner G, Pilicheva B, Marinova A, Viraneva A, Bodurov I, Sotirov S, Vlaeva I, Uzunova Y, Yovcheva T: Effect of assembly pH and ionic strength of chitosan/casein multilayers on benzydamine hydrochloride release, International Journal of Polymeric Materials and Polymeric Biomaterials, Volume 68, Issue 1-3, 11 February 2019, Pages 90-98

13. Katsarov P, Pilicheva B, Uzunova Y, Gergov G, Kassarova M. Chemical cross-linking: A feasible approach to prolong doxylamine/pyridoxine release from spray-dried chitosan microspheres. Eur J Pharm Sci. 2018 Oct 15;123:387-394.

14. Georgieva Y., Katsarova M, Gercheva K., Bozov P., Dimitrova S. HPLC analysis of flavonoids from Scutellaria altissima. Bulgarian Chemical Communications, 2019, Vol. 51, Special Issue D, 119-123 IF 0.242



1. Uzunova Y., Determination of residual monomers after polymerization of dental composites, 2013

2. Dimitrova S., Identification and antioxidant activity of isoprenoids from psychrophilic yeast biomass, 2014

3. Katsarova M, Chemical composition, antioxidant potential and biological activity of plants with anxiolytic action, 2017